DNA Sequencing Platform

The Genome Center maintains a state-of-the-art Sequencing Platform equipped to support large-scale genetics and genomics research as well as clinical-grade diagnostic nucleic acid sequencing. This platform performs data generation for whole-genome sequencing (WGS), whole-exome sequencing (WES), full transcriptome sequencing (RNA-seq), and other genomic analyses.
Automated workflows for sample processing and sequencing library preparation coupled with the highest throughput DNA sequencers allow for high quality, cost-effective and timely data generation, thereby empowering large projects with hundreds or thousands of DNA or RNA samples.
ISO 15189 accreditation of the Sequencing Platform provides a laboratory environment capable of producing clinical grade sequencing data. Acknowledging the critical issue of speed to medical clinical diagnostics, the Sequencing Platform will offer a ‘fast turn-around time’ WES test, promising data generation from sample delivery to data delivery in 2 weeks.
The Sequencing Platform’s combined support of large-scale genomic analyses and clinically accredited sequencing will help to place Switzerland at the forefront of genomic-driven research, genomic medicine, and personalized health.
The Sequencing Platform service offerings in Spring 2021 are:
- RNA-seq using the Illumina TruSeq mRNA-seq and TruSeq Total RNA-seq reagents,
- WGS using the Illumina TruSeq PCR-free DNA reagents,
- WES using Twist Comprehensive Exome Panel reagents,
- Rapid turn-around WES using Twist Comprehensive Exome Panel reagents,
- Full flow cell sequencing of user-prepared libraries on the Illumina NovaSeq 6000 and HiSeq 4000 instruments,
- Support and services for WES, WGS, and RNA-seq clinical diagnostic sequencing.
The following are examples of service fees at the Health 2030 Genome Center DNA Sequencing Platform.
These fees are indicative only. For research purposes, a minimum number of samples is required. Please request a quote for diagnostic sequencing here.
Average Coverage or Cluster Number for Sample Set
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Minimum Coverage or Cluster Number for Each Sample
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30x WGS
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850 CHF
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950 CHF
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70x WES* (IDT library reagents)
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415 CHF
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475 CHF
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RNA-seq* - 10M reads (50PE)
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155 CHF
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RNA-seq* - 25M reads (50PE)
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230 CHF
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*Volume discounts available for WES and RNA-seq
TEAM

Chief Operations Officer
Lab Associate, Quality Manager
Lab Associate
Lab Associate